Leadership
Board of Directors
Partnering with Spruce
Spruce is dedicated to developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical need. We welcome discussion on strategic collaboration opportunities with companies that share our mission to advance novel therapies for patients impacted by rare endocrine disorders. For additional information, please contact us at partnering@nullsprucebiosciences.com.
Contact Us
Spruce Biosciences, Inc.
2001 Junipero Serra Boulevard
Suite 640
Daly City, California 94014 USA
info@sprucebiosciences.com

Richard King, M.B.A.
Chief Executive Officer
Richard has held executive leadership roles at a number of companies in the life sciences industry throughout his 30+ year career. Most recently, Richard was Chief Operating Officer at Adamas Pharmaceuticals, Inc., responsible for all operational aspects leading to the successful launch of a novel Parkinson’s disease medication. Prior to Adamas, Richard was Chief Operating Officer at The Scripps Research Institute, where he was responsible for strategic planning, business development, finance, human resources, facilities, information technology and research services. Richard previously served as President and Chief Executive Officer of AcelRx Pharmaceuticals, Inc., a specialty pharmaceutical company developing new pain medications. Prior to AcelRx, Richard was President of the biotechnology company Tercica, Inc. (later sold to the Ipsen Group), where he was instrumental in the commercial launch of Somatuline Depot (lanreotide) and Increlex™ (rhlGF-1). Richard received a B.Sc. in chemical engineering from the University of Surrey in the U.K. and an M.B.A. from the Manchester Business School in the U.K.

Samir Gharib, M.B.A.
Chief Financial Officer
Samir is a proven and experienced leader in the global biopharmaceutical arena who has demonstrated success in strategy and execution of transformative capital raises, strategic transactions, and support of commercial product launches. Over the course of his career, Samir has raised over $500 million from the private and public capital markets, including an IPO, to fund late-stage clinical development, pipeline expansion and commercialization. Most recently, Samir was Chief Financial Officer of Stemedica Cell Technologies, a global pharmaceutical company focused on the development and commercialization of allogeneic progenitor cell therapeutics for underserved medical conditions. Prior to Stemedica, Samir held executive finance roles at Revance Therapeutics, Inc. and Talon Therapeutics, Inc. Samir began his career in the Audit and Advisory practice at KPMG LLP, and subsequently in the Corporate Finance practice at CRC LLP. Samir received a B.S. and M.B.A. from the Haas School of Business at the University of California at Berkeley.

Rosh Dias, M.D., MRCP
Chief Medical Officer
Rosh brings more than 20 years of experience in the pharmaceutical and biotechnology industries across multiple geographies, working to commercialize medicines for patients across multiple therapeutic areas, including the achievement of blockbuster status for several medicines. Rosh joins Spruce most recently from Indivior, where he was the Chief Medical Officer for the past year. Prior to Indivior, Rosh has had long tenures at both Amgen and Novartis. At Amgen, he was Vice President of Global Scientific Affairs, leading global scientific affairs spanning Amgen’s entire product portfolio and Vice President, Head of Global Medical and Scientific affairs at Onyx. Prior to Onyx, Rosh spent a decade in various roles for Novartis, including senior Clinical Development and Medical Affairs roles in both the US and Australia, where he led a variety of clinical development and medical affairs efforts with a focus on oncology, hematology, and rare diseases. Rosh holds a Medical Doctor degree from Charing Cross and Westminster Medical School in the UK, and is a Member of the Royal College of Physicians through postgraduate qualification in Internal Medicine.

Chris Barnes, Ph.D.
Vice President, Biometrics and Project Leadership
Chris joined Spruce with over 15 years of drug development experience. Prior to joining Spruce, Chris served in various leadership roles across Biometrics, Project Leadership and Alliance Management at Theravance Biopharma US, most recently as Senior Director, Biostatistics, and Project Team Leader. Prior to Theravance, Chris held positions of increasing responsibility at Innoviva Inc., formerly Theravance Inc. Previously, Chris held positions at Santen Inc. and Gilead Sciences. During his career, Chris has contributed to the development and approval of several products for high-risk populations including Vibativ® in MRSA-associated pneumonia and Yupelri® inhalation solution for severe COPD as well as products for larger populations such as the Ellipta family of respiratory products (BREO, ANORO and TRELEGY). In addition, Dr. Barnes is an author in over 30 journal articles covering the fields of pulmonology, gastroenterology, endocrinology, clinical pharmacology and statistics. Chris earned his Ph.D. in Biostatistics from the University of Louisville School of Public Health and Information Sciences.

Marc Lesnick, Ph.D.
Vice President, Regulatory Affairs and Quality
Marc joined Spruce with over 20 years of experience in product development and regulatory affairs, with multiple prior successful marketing applications in the U.S. and EU. Marc has worked in a range of therapeutic areas and has experience with products at all stages of development. Prior to joining Spruce, Marc was the Senior Vice President of Regulatory Affairs and Quality at Cascadian Therapeutics until its acquisition by Seattle Genetics. Marc also served as the Senior Vice President, U.S. Regulatory Affairs, Global Development Projects at Shionogi, Inc., where he led the filing of a New Drug Application for Symproic® and oversaw the approval and launch of Osphena® in the field of women’s health. In an earlier role at Optimer Pharmaceuticals, Marc led the approval of Dificid® in the U.S. and EU. Marc received his Ph.D. in Molecular Biology from the University of Oregon and performed his post-doctoral work at the University of California San Diego School of Medicine.

David Moriarty, Ph.D.
Vice President, Development Operations
David joined Spruce with 18 years of clinical industry experience. Prior to joining Spruce, David served as Vice President of Clinical Operations and Data Management at Jazz Pharmaceuticals, where he assembled a successful clinical operations, data management and strategic outsourcing team delivering multiple submissions in hematology/oncology and sleep medicine, leading to approvals for Defitelio and Vxyeos. Before Jazz, David was responsible for leading clinical operations for Janssen Pharmaceutical’s Alzheimer’s Disease late-stage clinical programs. Earlier at Janssen, formerly Tibotec Therapeutics, David held clinical operations roles leading to the approved HIV therapies of Prezista and Edurant. David also previously held positions of increasing responsibility at PPD, a global contract research organization, working primarily on the late development work of Humira for Abbott Pharmaceuticals. David earned a B.Sc. in Neuroscience from University of Central Lancashire in the U.K. and a Ph.D. in Neuroscience from the University of Manchester in the U.K.

Dasharatha Reddy, Ph.D.
Vice President, Pharmaceutical Development and Manufacturing
Dasharatha (Dash) joined Spruce with over 25 years of experience in the pharmaceutical development of small molecules from discovery to commercialization. Prior to joining Spruce, Dash served as Head of Chemistry, Manufacturing, and Controls (CMC) at Landos Biopharma. Before Landos, Dash was responsible for leading pharmaceutical development and manufacturing operations at Reviva Pharmaceuticals, with a focus on products for the treatment of central nervous system disorders. Dash previously led the development of products leading to the approval of a New Drug Application under the 505(b)2 pathway at Teikoku Pharma USA. In earlier roles, Dash contributed to the development and approval of small molecules to treat a variety of diseases at Spectrum Pharmaceuticals, Relypsa, and Horizon Therapeutics. Dash earned his Ph.D. in Organic Chemistry from the Indian Institute of Science and performed post-doctoral research at Northwestern University.
Michael Grey
Executive Chairman
Mike has served as Chairman of the Spruce Biosciences board since 2017. Mike has founded several biotechnology companies and is currently chairman or executive chair of Mirum Pharmaceuticals, Inc., Amplyx Pharmaceuticals, Inc. and Reneo Pharmaceuticals, Inc.. He also serves as venture partner at Pappas Capital. Previously, Mike founded and was President and Chief Executive Officer at Lumena Pharmaceuticals, Inc., a company developing treatments for pediatric and adult orphan diseases, until its acquisition by Shire Plc. Mike has 40 years of experience in the pharmaceutical and biotechnology industries, and has held senior positions at a number of companies, including President and Chief Executive Officer of Auspex Pharmaceuticals, Inc., President and Chief Executive Officer of SGX Pharmaceuticals, Inc., which was acquired by Eli Lilly in 2008, President and Chief Executive Officer of Trega Biosciences, Inc., which was acquired by Lion Bioscience in 2001, and President of BioChem Therapeutic Inc. For approximately 20 years, Mike served in various roles with Glaxo, Inc. and Glaxo Holdings plc, culminating in his position as Vice President, Corporate Development and Head of International Licensing. Mike serves on the Board of Directors of BioMarin Pharmaceutical Inc., Horizon Therapeutics plc, and Mirati Therapeutics, Inc.
Richard King, M.B.A.
Spruce Biosciences
Chief Executive Officer
Richard has held executive leadership roles at a number of companies in the life sciences industry throughout his 30+ year career. Most recently, Richard was Chief Operating Officer at Adamas Pharmaceuticals, Inc., responsible for all operational aspects leading to the successful launch of a novel Parkinson’s disease medication. Prior to Adamas, Richard was Chief Operating Officer at The Scripps Research Institute, where he was responsible for strategic planning, business development, finance, human resources, facilities, information technology and research services. Richard previously served as President and Chief Executive Officer of AcelRx Pharmaceuticals, Inc., a specialty pharmaceutical company developing new pain medications. Prior to AcelRx, Richard was President of the biotechnology company Tercica, Inc. (later sold to the Ipsen Group), where he was instrumental in the commercial launch of Somatuline Depot (lanreotide) and Increlex™ (rhlGF-1). Richard received a B.Sc. in chemical engineering from the University of Surrey in the U.K. and an M.B.A. from the Manchester Business School in the U.K.
Tiba Aynechi, Ph.D.
Novo Ventures
Partner
Tiba has served as a director on the Spruce Biosciences board since 2016. Tiba is a senior partner at Novo Ventures (US) Inc., joining the company in 2010. Tiba’s experience spans research, banking, and venture investing in life sciences across various therapeutic areas and technology platforms. Tiba serves on the boards of Mirum Pharmaceuticals, Allievex, Avalyn Biosciences, Nkarta Therapeutics, Arcellx Inc, MDLive, and Aristea Therapeutics. Tiba previously served as a board member for AnaptysBio (IPO 2017), iRhtyhm Technologies (IPO 2016), and Cianna Medical (acquired 2018). Prior to joining Novo A/S, Tiba was a Director with Burrill & Company, where she completed regional and cross-border M&A, licensing, and financing transactions for biotech and large pharmaceutical companies. Tiba is also a published author of scientific articles and book chapters in the area of rational drug design. Tiba received her Ph.D. in biophysics at the University of California, San Francisco where her research involved developing computational methods for drug discovery. Tiba has a B.S. in physics from the University of California, Irvine.
Dina Chaya, Ph.D., CFA
Omega Funds
Advisor
Dina is a Partner with NeoMed Management and Advisor to Omega Funds. Dina has been investing in the private equity and venture capital healthcare industry in Europe and the U.S. since 2001. Previously at 3i plc in London and Index Ventures in Geneva, Dina’s successful investments include Endosense, EUSA Pharma, Novexel and Wilson Therapeutics. Dina serves on the Board of Directors of Imago BioSciences, Oxular and TopiVert and is a member of the Venture Capital Platform Council of Invest Europe. Dina is a CFA charter holder and holds a Ph.D. degree in molecular and cellular biology from Paris VI University, France and carried out postdoctoral research at Brown University and at the Fox Chase Cancer Centre in Philadelphia.
Jonas Hansson
HealthCap
Partner
Jonas is a Partner with HealthCap, a life focused venture capital firm. Prior to joining HealthCap as a medical associate in 2008, Jonas held various sales and marketing positions within Janssen Pharmaceutical (J&J). Jonas received his M.Sc. in Pharmacy from Uppsala University and his master thesis was presented at The Scripps Research Institute in La Jolla, California. Jonas also holds an M.B.A. from Stockholm School of Economics. Jonas was the co-founder and Chief Executive Officer of HealthCap start-up Wilson Therapeutics AB, acquired by Alexion Pharmaceuticals, Inc. in 2018.
Bali Muralidhar, Ph.D.
Partner, Abingworth LLP
Bali is a partner at Abingworth LLP. Bali has 15 years professional experience in healthcare across a range of functions including venture investing, R&D and clinical practice. Prior to joining Abingworth, Bali was a senior partner at MVM Partners LLP where he sat on a number of boards, public and private. In 2018, Bali was named among Financial News’ Rising Stars in Private Equity, which celebrated 25 men and women under the age of 40 standing out in the European private equity industry. Before MVM, Bali was a member of Bain Capital’s healthcare deal team. Bali obtained a degree in clinical medicine from the University of Oxford and practiced general surgery at the John Radcliffe and Addenbrooke’s Hospitals in Oxford and Cambridge, respectively. Bali has a Ph.D. in translational cancer research from the MRC Cancer Cell Unit, University of Cambridge, and has published over a dozen peer reviewed papers. Mr. Muralidhar was also a Bye-Fellow in Medical Sciences at Downing College, Cambridge where he taught pathology, surgery and medicine.
Niall O’Donnell, Ph.D., M.B.A.
RiverVest Venture Partners
Partner
Niall has served as a Director of the Spruce Biosciences board since 2016. Niall is a partner at RiverVest Venture Partners, joining as a Kauffman Fellow in 2006. Niall is a board member of Mirum Pharmaceuticals, Amplyx Pharmaceuticals, Curzion Pharmaceuticals, and Avalyn Pharma, and a co-founder and Chief Executive Officer of Reneo Pharmaceuticals. Niall was previously a board member and adviser to Lumena Pharmaceuticals (acquired by Shire), Excaliard Pharmaceuticals (acquired by Pfizer) and Ziarco Group Limited (acquired by Novartis). Prior to joining RiverVest, Niall was in drug development at Johnson & Johnson Pharmaceutical Research and Development. Niall earned his Ph.D. in biochemistry from the University of Dundee, and an MA in natural sciences from Pembroke College, Oxford. Niall also earned an M.B.A. from the Rady School of Management at the University of California, San Diego.
Camilla V. Simpson, M.Sc.
Independent
Camilla has served as a director of the Spruce Biosciences board since 2017. Camilla has 24+ years in the life sciences industry. Camilla has significant experience in global drug development and registration, due diligence and M&A plus leadership of globally based teams, talent and change management. Camilla is currently Managing Member and President of Rare Strategic, LLC where she provides strategic advice to private rare disease and gene therapy companies. Previously, Camilla was Senior Vice President and Head of Product Portfolio Development at BioMarin, where she was responsible for Corporate and R&D Governance, Program Leadership, Project Management, Competitive Intelligence, Portfolio Strategy and Business Analytics. Prior to leading Product Portfolio Development, Camilla led BioMarin’s Global Regulatory Affairs group. Previously, Camilla spent 12 years at Shire Pharmaceuticals, where after multiple roles of increasing responsibility, held the position of Vice President, Regulatory Affairs and Early Development and Business Development. Before Shire, Camilla spent seven years at Abbott Laboratories. Camilla holds a BS.c. from University College Galway, Ireland, BS.c Hons from Kingston University, U.K. and an MSc with distinction from the University of London.
Dan Spiegelman, M.B.A.
Independent
Dan is an accomplished executive with extensive commercial, financial and strategic leadership experience during an extensive career in the pharmaceutical industry, with a specific focus on rare diseases. Dan previously served as Executive Vice President and Chief Financial Officer of BioMarin. Prior to BioMarin, he served as a consultant to provide strategic financial management support to a portfolio of public and private life science companies. Prior to his consultancy, Dan served as Senior Vice President and Chief Financial Officer of CV Therapeutics. Prior to CV Therapeutics, he served in various roles at Genentech, most recently as Treasurer. Dan currently serves on the boards of directors for Myriad Genetics, Recardia Therapeutics and Tizona Therapeutics. He received a B.A. from Stanford University and an M.B.A. from the Stanford Graduate School of Business.
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