Our clinical trials of tildacerfont in adults with classic CAH, CAHmelia 203 and CAHmelia 204, are open for screening | LEARN MORE


At Spruce, patients are at the center of everything we do. Individual experiences and stories motivate us to continue innovating and striving toward delivering well-tolerated and effective treatments to address the needs of people living with rare endocrine disorders like CAH. Spruce is developing a potentially novel treatment approach to address the difficult physical and mental hurdles patients undergo each and every day, some of which are shown below. We aim to overcome the demonstrated medical need for a classic CAH treatment that manages the disease without harmful side effects.

Endocrinologist Quote

High doses of steroids can cause serious complications over a lifetime. Patients should understand that over-medication or improper balance of steroids is a real problem. Some of the physical symptoms do not appear for a long time.”

Patient Stories

Patient Stories